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在透射电镜下,我们观察到PVN大细胞具有四种不同的形态,认为属于同一类细胞分泌活性的不同时相:(1)合成相,粗面内质网非常丰富,(2)加工相:Golgi复合体发达,周围分布着一些神经分泌颗粒;(3)储存相:神经分泌颗粒明显增多:(4)转运相:细胞质内神经分泌颗粒很少,而在细胞周围可见一些充满神经分泌颗粒的突起。免疫电镜的结果也证实了VP阳性神经细胞具有类似的四种不同形态,其中在合成相,粗面内质网囊膜呈免疫阳性反应,还有一些PAP免疫复合物沉积在细胞质中。而在加工,储存和转运相,神经分泌颗粒呈免疫阳性反应。同样,小细胞亦具有三种不同形态特证,可能代表着不同的功能状态。
Under transmission electron microscopy, we observed that PVN macrophages have four different morphologies and are considered to belong to different phases of the same type of cell secretory activity: (1) synthetic phase, abundant rough endoplasmic reticulum, (2) processing phase: Golgi complex developed around the distribution of a number of neurosecretory particles; (3) storage phase: neurosecretory particles was significantly increased: (4) transport phase: few cytoplasmic neurosecretory particles, and in the surrounding cells can see some filled with neurosecretory particles Prominent. Immunoelectron microscopy also demonstrated that VP-positive neurons had four similar morphologies, with immunopositive reactions in the synovial membrane of the rough endoplasmic reticulum, and some of the PAP immune complexes were deposited in the cytoplasm. In processing, storage and transport phase, neurosecretory granules were immunopositive. Similarly, small cells also have three different morphological characteristics, may represent different functional status.