论文部分内容阅读
目的:分析不同血氧饱和度对早产儿视网膜病(ROP)发病率的影响。方法:选择2010年1月到2012年12月我院NICU收治的650例早产儿作为研究对象,根据平均血氧饱和度水平将早产儿分为低血氧饱和度组409例(SaO291%~95%)和高血氧饱和度组241例(SaO296%~100%),观察住院期间血氧饱和度和视网膜病发病率的情况。结果:高血氧饱和度组早产儿ROP发病率18.1%,高于低血氧饱和度组的发病率的4.6%(P<0.01),并且高血氧饱和度组早产儿ROP各期的患病例数都明显高于低血氧饱和度组早产儿(P<0.05)。Logistic多元回归分析结果显示,高血氧饱和度早产儿ROP发病相对危险度值最高(OR=2.674,95%CI:1.246,6.554)。结论:早产儿吸氧时血氧饱和度应尽量控制在91%~95%之间,否则可增加ROP的发生。
Objective: To analyze the effect of different oxygen saturation on the incidence of retinopathy of prematurity (ROP). Methods: From January 2010 to December 2012, 650 preterm infants from NICU in our hospital were selected as study subjects. Preterm infants were divided into 409 cases (44%) according to the average oxygen saturation level %) And high oxygen saturation group 241 cases (SaO296% ~ 100%), observation of oxygen saturation during hospitalization and the incidence of retinopathy. Results: The incidence of ROP in preterm infants with high oxygen saturation was 18.1%, which was 4.6% higher than that in patients with low oxygen saturation (P <0.01), and the incidence of ROP in high oxygen saturation group The number of cases were significantly higher than those in hypoxemia group (P <0.05). Logistic multivariate regression analysis showed that the relative risk of ROP was highest in high oxygen saturation preterm infants (OR = 2.674, 95% CI: 1.246, 6.554). Conclusion: The oxygen saturation of oxygen in premature infants should be controlled as much as 91% -95%, otherwise the ROP may be increased.