论文部分内容阅读
1922年,Groover首次论述了放射治疗对肺和胸膜的不利效应,随即Hines报告了辐射诱发肺脏损伤的病例。之后在这60年的过程中许多学者深入地研究了实验性及放射治疗后的放射性肺炎与肺纤维化。Rajewsky报告1例从事配制放射性发光涂料的实验室工作人员,历时三年后发生了致命性放射性肺炎。Rall亦曾观察到15例甲状腺癌肺转移病人用大剂量放射性碘治疗而引起严重肺损伤,其中2例死于本病,另4例有肺纤维化的X线所见。为了增加对放射性肺损伤的注意,采取预防及治疗措施,现将近年来有关文献综述如下。
In 1922, Groover first discussed the adverse effects of radiation therapy on the lungs and pleura, and Hines then reported on radiation-induced lung injury. After that, during the 60 years, many scholars studied in depth the experimental and radiation-induced radiation pneumonitis and pulmonary fibrosis. Rajewsky reports 1 case of laboratory staff working on the preparation of radioluminescent coatings that killed lethal radiation pneumonitis three years later. Rall also observed 15 patients with lung metastasis of thyroid cancer treated with high-dose radioactive iodine caused severe lung injury, of which 2 died of this disease, and the other 4 cases of pulmonary fibrosis seen in the X-ray. In order to increase attention to radiation-induced lung injury and take preventive and therapeutic measures, the relevant literature in recent years is summarized as follows.