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目的:探究分析双歧杆菌三联活菌胶囊对幽门螺杆菌感染消化性溃疡的治疗及其效果。方法:选取2015年01月0l日到2016年12月31日我院于我院资料的幽门螺杆菌感染消化性溃疡患者42例为研究对象。随机分为选择常规抗幽门杆菌三联治疗的对照组(21例),与选择双歧杆菌三联活菌胶囊治疗的观察组(21例),测定两组治疗前和治疗后患者胃液的PH值,再比较分析两组患者4周后溃疡及糜烂的治愈情况和不良反应发生率、Hp根除率。结果:经过治疗后,观察组与对照组患者PH较比治疗前均有明显改善,且效果显著(P<0.05)。且两组患者PH值没有显著差异(P>0.05)。观察组患者4周后溃疡的治愈率80.95%,与对照组患者溃疡治愈率76.19%,无明显差异(P>0.05)。观察组患者糜烂的治愈率为66.67%,明显优于对照组的糜烂治愈率42.86%,差异显著(P<0.05)。观察组患者的不良反应发生2例,占9.52%,明显低于对照组患者不良反应发生7例,占33.33%(P<0.05)。观察组患者的Hp根治率明显优于对照组(P<0.05)。结论:选择双歧杆菌三联菌胶囊对幽门螺杆菌感染消化性溃疡的治疗,可有效改善患者的溃疡状态,提升患者糜烂愈合水平,降低并发症发生,并有效提升Hp根治率,效果显著,值得临床推广实践。
Objective: To investigate the treatment of peptic ulcer caused by Helicobacter pylori and its effects by analyzing Bifidobacterium triple viable capsule. Methods: Forty-two patients with Helicobacter pylori infection peptic ulcer were selected from January 01, 2015 to December 31, 2016 in our hospital. Randomly divided into control group (21 cases) selected routine anti-H pylori triple therapy and control group (21 cases) selected Bifidobacterium triple viable capsule treatment group. The PH value of gastric juice in both groups before and after treatment was measured, Then a comparative analysis of two groups of patients after 4 weeks of ulcer and erosion of the cure and the incidence of adverse reactions, Hp eradication rate. Results: After treatment, PH in observation group and control group were significantly improved compared with that before treatment, and the effect was significant (P <0.05). There was no significant difference between the two groups (P> 0.05). The curative rate of ulcer in observation group was 80.95% after 4 weeks, and that in control group was 76.19%. There was no significant difference (P> 0.05). The curative rate of erosions in the observation group was 66.67%, which was significantly better than that of the control group (42.86%), the difference was significant (P <0.05). Adverse reactions in observation group occurred in 2 cases (9.52%), which was significantly lower than that in control group (7 cases), accounting for 33.33% (P <0.05). The observation group patients Hp radical cure rate was significantly better than the control group (P <0.05). Conclusion: The treatment of H.pylori infection with peptic ulcer by Bifidobacterium triple inoculation capsule can effectively improve the patient’s ulcer status, improve the healing of patients with erosion, reduce the incidence of complications and effectively improve the cure rate of Hp, the effect is remarkable, it is worth Clinical practice.