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肝纤维化是指临床肝病因为各种致病引子导致肝内结缔组织出现异常增生,细胞外基质代谢异常引发的结缔组织重建。由于肝纤维化是一个动态变化的过程中,肝纤维化早期可能有逆转性,因此针对肝纤维化要早发现、早治疗,这样才能抓住肝硬化康复的时机。目前针对肝纤维化的诊断方法主要由血清学、影像学以及病理学三种,其中血清学是当前临床应用最广泛的方式,本文主要探讨肝纤维化检验血清学检测指标的研究现状和研究进展。
Liver fibrosis refers to the clinical liver disease because a variety of pathogenic leads lead to abnormal proliferation of intrahepatic connective tissue, extracellular matrix metabolism caused by connective tissue remodeling. As liver fibrosis is a dynamic process of change, liver fibrosis early may have reversal, so early detection and treatment of liver fibrosis, so as to seize the opportunity of liver cirrhosis rehabilitation. The current diagnosis of liver fibrosis mainly by serological, imaging and pathology of three, including serology is currently the most widely used clinical approach, this paper mainly discusses the status of liver fibrosis test serological indicators and research progress .