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目的:观察四联补救疗法联合自拟清胃健脾汤治疗耐药幽门螺杆菌相关消化性溃疡的疗效。方法:对照组54例使用四联补救疗法,然后再服用奥美拉唑20 mg,2次/d,连服4周;治疗组66例用自拟清胃健脾汤联合四联补救疗法治疗。结果:治疗组总有效率明显高于对照组,胃镜下溃疡愈合率明显高于对照组,幽门螺杆菌根除率明显高于对照组,不良反应总发生率明显低于对照组。结论:自拟清胃健脾汤联合四联补救疗法治疗耐药幽门螺杆菌相关消化性溃疡有明显优势。
Objective: To observe the curative effect of quadruple salvage therapy combined with self-made Qingwei Jianpi decoction in the treatment of H. pylori-associated peptic ulcer. Methods: The control group of 54 patients with quadruple salvage therapy, and then taking omeprazole 20 mg, 2 times / d, and even for 4 weeks; 66 cases of treatment group with self-Qingwei spleen soup combined quadruple salvage therapy . Results: The total effective rate of the treatment group was significantly higher than that of the control group. The healing rate of gastric ulcer was significantly higher than that of the control group. The eradication rate of Helicobacter pylori was significantly higher than that of the control group. The incidence of adverse reactions was significantly lower than that of the control group. Conclusion: Self-made Qingwei Jianpi Decoction combined quadruple salvage therapy for the treatment of drug-resistant Helicobacter pylori-associated peptic ulcer has obvious advantages.