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磷脂酰肌醇蛋白聚糖3(GPC3)是磷脂酰肌醇蛋白家族的一个成员,通过磷脂酰肌醇糖基锚定在细胞膜硫酸类肝素粘蛋白上,已有报道用于肝癌的血清学和免疫组化诊断标记物。而在小肝癌和其癌前病变和良性肝病变组织中的表达尚无报道。作者应用免疫组化评价了GPC3在几种肝病变组织中的表
Glypican 3 (GPC3), a member of the phosphatidylin family, is anchored to the plasma membrane of heparan sulfate mucin by glypican, which has been reported for serological and Immunohistochemistry diagnostic marker. However, the expression in small hepatocellular carcinoma and its precancerous lesions and benign liver lesions has not been reported yet. The authors used immunohistochemistry to evaluate GPC3 expression in several liver lesions