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目的：研究阿托伐他汀钙抗颈动脉粥样硬化的应用效果。方法：选择2015年2月至2016年3月期间我院收治的60例颈动脉粥样硬化的患者，并将其分为试验组（n=30）和对照组（n=30），对照组患者采取阿司匹林肠溶片治疗，试验组患者在此基础上进行阿托伐他汀治疗，比较两组患者的治疗效果。结果：治疗后，试验组患者颈动脉粥样硬化程度、狭窄程度、软斑以及溃疡斑块的发生率明显低于对照组，且不良反应发生率以及脑梗死复发率明显低于对照组，两组比较差异具有统计学意义（p<0.05）。结论：阿托伐他汀钙抗颈动脉粥样硬化的应用效果较好，能够显著降低脑梗死的复发率，有效改善患者的血脂水平，减少治疗过程中的不良反应，是一种安全有效的治疗方法，值得在临床上推广应用。“,”Objective: To study the effect of atorvastatin calcium on carotid atherosclerosis.Methods: 60 cases of patients with carotid atherosclerosis in our hospital during February 2015 to March 2016, and divided into the experimental group (n=30) and control group (n=30), the control group was taken with the Aspirin Enteric-coated Tablets treatment, patients in the experimental group on the basis of atorvastatin treatment, compared two groups of patients. Results:after treatment, the degree of atherosclerosis in patients with carotid stenosis, test, soft plaque and ulcer plaque was significantly lower than the control group, and the incidence of adverse reactions and recurrence of cerebral infarction was significantly lower than the control group, with significant differences between the two groups (p<0.05). Conclusion:good application effect of atorvastatin calcium on carotid atherosclerosis, cerebral infarction can significantly reduce the recurrence rate, improve the blood lipid level of patients, reduce the adverse reaction during the treatment, is a safe and effective treatment, worthy of clinical application.