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目的探讨血清中食物过敏原特异性IgE、IgG抗体与小儿腹泻的关系。方法选取2006年3月至2007年5月经大便镜检和培养排除寄生虫和细菌感染的急性腹泻患儿组32例;慢性腹泻患儿组38例;正常对照组20例。分别检测其血清中食物特异性IgE、IgG抗体水平。结果食物过敏原特异性IgE抗体检测,急性腹泻患儿组、慢性腹泻组、正常对照组阳性率分别为40.6%、5.6%、5.0%;食物过敏原特异性IgG抗体检测,慢性腹泻患儿组、急性腹泻组、正常对照组阳性率分别为97.2%、9.4%、5.0%。结论检测食物特异性IgE、IgG抗体分别在小儿急、慢性腹泻诊治中有重要意义。
Objective To investigate the relationship between serum allergen-specific IgE and IgG antibodies in children with diarrhea. Methods Thirty-two children with acute diarrhea who underwent microscopic stool examination and culture to exclude parasites and bacterial infection from March 2006 to May 2007 were selected; 38 children with chronic diarrhea and 20 normal controls. The serum levels of food-specific IgE and IgG were detected respectively. Results The positive rates of food allergen-specific IgE antibody test, acute diarrhea children group, chronic diarrhea group and normal control group were 40.6%, 5.6% and 5.0%, respectively. Food allergen-specific IgG antibody test and chronic diarrhea children group , Acute diarrhea group and normal control group were 97.2%, 9.4%, 5.0% respectively. Conclusion Detection of food-specific IgE, IgG antibodies in children with acute and chronic diarrhea, diagnosis and treatment of great significance.