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目的:探究缬沙坦与氨氯地平对社区老年原发性高血压并糖尿病的治疗效果。方法:选取我院自2015年5月至2017年5月间诊治的100例社区原发性高血压并糖尿病老年患者作为研究对象,并随机分为对照组和观察组,每组各50例,对照组患者接受缬沙坦单独治疗,观察组患者接受缬沙坦联合氨氯地平治疗,连续治疗2个月,观察并比较两组原发性高血压并糖尿病老年患者的临床应用效果。结果:观察组患者的空腹血糖含量、饭后2小时血糖含量、以及血压情况均明显优于对照组患者的空腹血糖含量、饭后2小时血糖含量、以及血压情况,差异具有统计学意义(p<0.05)。结论:缬沙坦联合氨氯地平治疗应用于老年原发性高血压并糖尿病患者能够明显改善患者的临床指标,且安全性高,值得今后在临床工作中进行推广应用。
Objective: To investigate the therapeutic effects of valsartan and amlodipine on elderly patients with essential hypertension and diabetes mellitus. Methods: A total of 100 elderly patients with primary hypertension and diabetes mellitus who were diagnosed and treated in our hospital from May 2015 to May 2017 were selected as study subjects and randomly divided into control group and observation group, 50 cases in each group, Patients in the control group received valsartan alone. Patients in the observation group received valsartan combined with amlodipine for 2 months. The clinical effects of the two groups of patients with essential hypertension and diabetes mellitus were observed and compared. Results: The fasting blood glucose level, fasting blood glucose levels at 2 hours after meal and blood pressure were significantly higher in the observation group than those in the control group (P <0.05). The levels of fasting blood glucose at 2 hours after meal and blood pressure were significantly different (p <0.05). Conclusion: The combination of valsartan and amlodipine in elderly patients with essential hypertension and diabetes mellitus can significantly improve the clinical indicators of patients with high safety. It is worth to be popularized and applied in clinical work in the future.