细针活组织检查诊断虹膜环黑色素瘤

• 作 者: Char D.H. Kemlitz A.E. Miller T. Crawford J.B. 王静波
• 机 构: Tumori Foundation 45 Castro Street,San Francisco,CA 94114,United States Dr.,
• 出 处: 世界核心医学期刊文摘.眼科学分册
• 发表日期: 2006年09期
• 关键词: 细针活组织检查 虹膜环 黑色素瘤 肿瘤死亡率 虹膜 生存分析 前房角 局部肿瘤 活组织检查 新生物

Aims:To delineate the diagnostic accuracy of fine needle biopsy in iris ring melanoma and determine the tumour related mortality of this neoplasm.Methods:A retrospective analysis of 22 patients with iris melanomas that involve the entire 360 degrees of the anterior chamber angle.Results:Iris ring melanomas were correctly diagnosed in all cases.In 11 of 16 cases(69%)a fine needle biopsy performed 180 degrees away from the main mass was positive for an iris ring melanoma.The tumour related mortality in iris ring melanoma cases was four of 22 patients(18%).Actuarial survival analysis showed a 10 year mortality(Kaplan-Meier)of 15%.Conclusion:A fine needle aspiration biopsy can be used to diagnose an iris ring melanoma.Iris ring melanomas have significant mortality compared with focal tumours.

Aims: To delineate the diagnostic accuracy of fine needle biopsy in iris ring melanoma and determine the tumor related mortality of this neoplasm. Methods: A retrospective analysis of 22 patients with iris melanomas that involve the entire 360 ​​degrees of the anterior chamber angle. Results: Iris ring melanomas were correctly diagnosed in all cases. 11 of 16 cases (69%) a fine needle biopsy performed 180 degrees away from the main mass was positive for an iris ring melanoma.The tumor related mortality in iris ring melanoma cases was four of 22 patients (18%). Actuarial survival analysis showed a 10 year mortality (Kaplan-Meier) of 15% .Conclusion: A fine needle aspiration biopsy can be used to diagnose an iris ring melanoma.Iris ring melanomas have significant mortality compared with focal tumours.