Synthesis of Asymmetric 4H-1, 3, 2-Benzodioxaphosphorin 2-Sulfides from Intramolecular Cyclization

• 出 处: Chinese Chemical Letters
• 发表日期: 1999年09期
• 关键词: substituted methoxy editorial figure Sulfur stereo Cleveland

Asymmetric 6-substituted-2-methoxy-4-(2,4-dichlorophenyl)-4H,3,2-benzodioxa-phosphorin 2-sulfides were prepared tyom intramolecular cyclization. The diastereomers wereseparated by column chromatography and fractional crystallization. Their structures werecharacterized on the basis of 1 H NMR. 31 P NMR and x-ray diffraction analysis.

Asymmetric 6-substituted-2-methoxy-4- (2,4-dichlorophenyl) -4H, 3,2-benzodioxa-phosphorin 2-sulfides were prepared by intramolecular cyclization. The diastereomers were prepared by column chromatography and fractional crystallization. on the basis of 1 H NMR. 31 P NMR and x-ray diffraction analysis.