论文部分内容阅读
目的探讨生长抑素联合泮托拉唑治疗上消化道出血的临床疗效。方法选取2014年10月—2015年12月南漳县板桥镇中心卫生院内科收治的上消化道出血患者118例,按照随机数字表法分为研究组与对照组,各59例。对照组给予生长抑素治疗,研究组给予生长抑素联合泮托拉唑治疗。比较两组患者治疗总有效率、不良反应发生率和出血时间。结果研究组患者总有效率为94.9%(56/59),高于对照组的79.7%(47/59),差异有统计学意义(P<0.05);研究组患者不良反应发生率为10.2%(6/59),对照组患者不良反应发生率为11.9%(7/59),组间比较,差异无统计学意义(P>0.05);研究组患者出血时间为(44.9±9.3)h,短于对照组的(56.5±10.0)h,差异有统计学意义(P<0.05)。结论生长抑素联合泮托拉唑治疗上消化道出血的临床疗效显著,且不良反应少。
Objective To investigate the clinical efficacy of somatostatin combined with pantoprazole in the treatment of upper gastrointestinal bleeding. Methods From October 2014 to December 2015, 118 patients with upper gastrointestinal hemorrhage admitted in Banqiao Central Hospital of Nanzhang County were divided into study group and control group according to the random number table method, with 59 cases in each group. The control group was given somatostatin, and the study group was given somatostatin plus pantoprazole. The total effective rate, incidence of adverse reactions and bleeding time were compared between the two groups. Results The total effective rate was 94.9% (56/59) in the study group, which was significantly higher than that in the control group (79.7%, 47/59) (P <0.05). The incidence of adverse reactions in the study group was 10.2% (6/59) in the control group, and 11.9% (7/59) in the control group. There was no significant difference between the two groups (P> 0.05). The bleeding time in the study group was (44.9 ± 9.3) h, Shorter than that in the control group (56.5 ± 10.0) h, the difference was statistically significant (P <0.05). Conclusion Somatostatin combined with pantoprazole in the treatment of upper gastrointestinal bleeding clinical efficacy was significant, and less adverse reactions.