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为了阐明胆酸在应激性溃疡发病中的作用,作者进行了如下的实验性研究。方法:自狗的胃近端部取出一带蒂的胃壁楔状片,其血供与肠系膜和脾血管相连,放置在甲基丙烯酸制成的盒内。 (一)测定粘膜功能的项目 (1)H~+、Na~+、K~+和Cl~-的纯净移动(以△H~+、△Na~+等表示);(2)胃腔和血液之间电位差(PD);(3)粘膜血流量;(4)
In order to elucidate the role of bile acids in the pathogenesis of stress ulcer, the authors conducted the following experimental studies. METHODS: A pedicled wedge-shaped piece of stomach wall was taken from the proximal part of the stomach of a dog whose blood supply was connected to the mesentery and splenic vessels and placed in a box made of methacrylic acid. (1) Measurement of mucosal function (1) Pure movement of H ~ +, Na ~ +, K ~ + and Cl ~ - expressed by △ H ~ + and △ Na ~ +; Potential difference between blood (PD); (3) mucosal blood flow; (4)