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目前国内外对前列腺素E_2、F_(2α)及其类似物应用于早期妊娠抗早孕,中、晚期妊娠引产的报道较多,效果均较肯定。但是,应用前列腺素防治产后出血,国内尚未见报道。我院自1981年2月至1982年2月曾应用国产Dl-15甲基前列腺素F_(2α)(简称15甲PGF_(2α))宫体肌注观察足月产后子宫收缩状况7例,效果相当满意,介绍如下: 案例一、剖腹产术时子宫肌壁注射15甲PGF_(2α)观察局部及全身反应共4例。例1、2在胎儿娩出后以15甲PGF_(2α)1mg缓慢注入宫体前壁。发现在注射后局部立即收缩呈灰白色,并向整个宫体扩散,宫体变硬,浆膜皱缩,血压迅速一过性上升,约一刻
At present, there are many reports on the application of prostaglandin E_2, F_ (2α) and its analogs in early pregnancy with early pregnancy, middle and late pregnancy. However, the application of prostaglandin to prevent postpartum hemorrhage, has not been reported in China. Our hospital from February 1981 to February 1982 had applied domestic Dl-15 methyl prostaglandin F_ (2α) (referred to as 15 A PGF_ (2α)) intrauterine myometrial observation of full-term postpartum uterine contractions in 7 cases, the effect Very satisfied, described as follows: Case 1, caesarean section intramuscular injection of 15 A PGF_ (2α) observed in 4 cases of local and systemic reactions. Cases 1 and 2 were injected slowly into the anterior wall of the uterine antrum with 15 mg of PGF_ (2α) 1 mg after the fetus was delivered. Immediately after injection in the local contractions were found to be gray-white, and spread to the entire palace, the palace hardened, serosal collapse, rapid rapid increase in blood pressure, about a moment