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目的 :研究羊膜移植治疗大泡性角膜病变的疗效.方法 :对 15例 (15只眼 )大泡性角膜病变患者采用羊膜移植治疗.其中无晶状体眼 5例 ,人工晶状体眼 5例 ,有晶状体眼者 3例 ,角膜移植片失败者 2例.结果 :随访期 3~ 12个月 ,治疗后1~ 3天内症状解除者 13例 (86 6 7%) ,症状减轻者 2例 ,所有患者角膜上皮缺损在 3~ 4周内愈合.结论 :羊膜移植能有效地控制大泡性角膜病变的症状 ,促进上皮愈合 ,且安全、简便、易行 ,具有很大的发展前途.“,”Objective:to evaluate the therapeutic effects of amniotic membrane transplantation (AMT)for bullous keratopathy.Methods:AMT was performed on 15 patients (15 eyes) with bullous keratopathy.The underlying causes of bullous keratopathy included aphakia(5 eyes)pseudophakia(5 eyes) failed corneal grafts(2 eyes) phakic eyes (3 eyes).Results:All patients had been followed up for 3 to 12 months.Within 1 to 3 days postoperatively symptoms of bullous keratopathy were relieved in 13 eyes and symptoms reduced in 2 eyes.Epithlial defects in all patients healed rapidly within 3 to 4 weeks.Conclusion:AMT relieves the symptoms effectively and promotes epithelial healing in bullous keratopathy.This method is simple and safe,and easily to perform if is highly recommanded for treatment of bullous keratopathy.