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急性肿瘤溶解综合征是由细胞的迅速溶解所致的突发性代谢表现:高血尿酸、高血钾;高血磷及高血钙。本征危及生命的并发症有:尿酸性急性肾功衰竭及心律不整,本征常见于下述血源性恶性肿瘤的化疗;包括淋巴瘤、尤其是 Burkitt 氏淋巴瘤和急性白血病,发生于非血源性恶性肿瘤的急性肿瘤溶解综合征是少见的。作者报告一例伴有转移性髓母细胞瘤的女性患者,在接受姑息性放疗时,腹部出现迅速增大的肿瘤,放疗总量为300拉德。个别病案报导,本征也可由转移性腺癌的自发性坏死所致。就作者所知,由转移性髓母细胞瘤所引起的急性肿瘤溶解综合征还是首例。
Acute lysis syndrome is a sudden metabolic manifestations caused by the rapid dissolution of cells: hyperuricemia, hyperkalemia; hyperphosphatemia and hypercalcemia. Intrinsic life-threatening complications include: Uric acid acute renal failure and arrhythmia, common in the following blood-borne malignancy chemotherapy; including lymphoma, especially Burkitt’s lymphoma and acute leukemia, occurred in non- Acute tumor lysis syndrome of blood-borne malignancies is rare. The authors report that in a woman with metastatic medulloblastoma, there was a rapidly expanding tumor in the abdomen on palliative radiotherapy with a total radiotherapy of 300 rads. Individual case reports, intrinsics may also be caused by spontaneous necrosis of metastatic adenocarcinoma. To the authors’ knowledge, acute lysis syndrome caused by metastatic medulloblastoma is the first case.