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目的分析药师干预对临床麻醉药品应用结构的影响。方法 2010—2012年溧阳市人民医院对临床使用的主要品种的麻醉药品处方实施药师干预,药师对临床麻醉药品处方的数量、疑议处方数量、用药频度、日均费用、患者用药情况等麻醉药品使用指标进行分析及干预,对疑议的处方及时向医师反馈。结果 2010—2012年麻醉药品处方数量占比分别为0.28%、0.29%、0.30%,差异无统计学意义(P>0.05)。2010年临床麻醉药品处方合格率为93.96%,2011年临床麻醉药品处方合格率为98.34%,2012年临床麻醉药品处方合格率为99.47%。2010—2012年盐酸哌替啶注射液、磷酸可待因片使用在患者麻醉药品使用中占比下降,盐酸吗啡缓释片、盐酸吗啡注射液和盐酸布桂嗪注射液在患者麻醉药品中占比上升。2010年与2012年麻醉药品DDDs比较,差异有统计学意义(P<0.05)。结论药师干预能有效改善临床麻醉药品中部分药品的结构比例,提升麻醉处方的合理性。
Objective To analyze the influence of pharmacist intervention on the application structure of clinical anesthetic drugs. Methods From 2010 to 2012, Liyang People’s Hospital conducted a pharmacist intervention on narcotic prescriptions of the main varieties of clinical use. The pharmacists conducted an anesthesia study on the number of prescriptions for clinical narcotic drugs, the number of suspected prescriptions, the frequency of medication, the average daily cost, and the patient’s medication status Drug use indicators for analysis and intervention, the proposed prescription prompt feedback to the physician. Results The proportion of prescriptions for narcotic drugs in 2010-2012 was 0.28%, 0.29% and 0.30%, respectively, with no significant difference (P> 0.05). The passing rate of clinical anesthetic prescriptions in 2010 was 93.96%. The passing rate of prescriptions for clinical anesthetic drugs in 2011 was 98.34%. The passing rate of prescriptions for clinical anesthetic drugs in 2012 was 99.47%. 2010-2012 Pethidine hydrochloride injection, codeine phosphate tablets in the use of narcotic drugs in patients with the proportion of decline, morphine hydrochloride sustained-release tablets, morphine hydrochloride injection and buzine hydrochloride injection in patients with narcotic drugs accounted for Than the rise. There was a significant difference between DDDs of narcotic drugs in 2010 and 2012 (P <0.05). Conclusion The intervention of pharmacists can effectively improve the structural proportion of some drugs in clinical anesthetics and improve the rationality of narcotic prescription.