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痛经在妇科疾病中最常见.痛经时子宫肌收缩增强宫内张力升高.目前认为:在痛经发生过程中,PG起主要作用.痛经患者的月经液中有高浓度的PG,用几种PG合成酶抑制剂治疗可以对抗.当然,可能还有其它因素参与,因为并非所有病人对此种治疗均有效,例如炎症前物质—缓激肽能增强PG的痛觉过敏效应.本文作者利用具有正常动情期的荷兰豚鼠研究PG、花生四烯酸等对子宫收缩和子宫交感神经系统的影响及PG合成酶抑制剂
Dysmenorrhea in gynecological diseases most common dysmenorrhea, uterine muscle contraction enhanced intrauterine tension is now that: in the process of dysmenorrhea, PG plays a major role in menstrual fluid in dysmenorrhea in patients with high concentrations of PG, with several PG Of course, there may be other factors involved, because not all patients are effective for this treatment, such as pre-inflammatory substances - bradykinin can enhance the hyperalgesic effect of PG. The author of the use of normal estrus Period of guinea pig study of PG, arachidonic acid on the uterine contraction and uterine sympathetic nervous system effects and PG synthase inhibitor