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作者曾连续报道从Crohn氏病的组织中分离到分枝杆菌,并从慢性消耗性腹泻的猴中分离到类似微生物,该分枝杆菌在肉汤中对链霉素、万古霉素、利福平、氯氟齐明、头孢唑啉、丁胺卡那霉素,Rifabutin和卡那霉素敏感。用丁胺卡那霉素治疗90天,用Rifabutin治疗12～22个月不等,使组织学和细菌学指标转为正常。作者进一步选用链霉素(肌注,每周5日,每日1克,治疗2～4月),同时每日给300mgRifabutin,对难治性
The authors have consecutively reported that mycobacteria were isolated from Crohn’s disease tissue and similar microbes were isolated from monkeys with chronic wasting diarrhea who were challenged with streptomycin, vancomycin, Rifabutin and kanamycin were sensitive to fluvoxamine, cefazolin, amikacin, rifabutin and kanamycin. Treatment with amikacin 90 days, with Rifabutin treatment 12 to 22 months, the histological and bacteriological indicators to normal. The authors further selected streptomycin (intramuscular injection, 5 days a week, daily 1 g, treatment 2 to April), while daily 300mgRifabutin, refractory