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早期妊娠因子(Early Pregnancy Factor、EPF)是新发现的一种在体外能抑制花结形成在体内具有免疫抑制活性的物质,在妊娠母血中在受精后的48小时之内就可测出,是妊娠的第一个信号,与胎儿不受母体排斥有关。我们利用标准化的花结抑制试验,对94例妊娠母血进行了测定,证明确实存在有EPF,在妊娠早期活性最强,随孕周的增加而降低,至分娩前8周消失。另外还测定过21例流产前后的孕妇血清,流产前血
Early Pregnancy Factor (EPF), a newly discovered substance that inhibits the formation of floral-knot in vitro and has immunosuppressive activity in vitro, can be detected in gestational maternal blood within 48 hours after fertilization, Is the first signal of pregnancy, and the fetus is not related to the exclusion of the mother. We tested for 94 gestational maternal blood using a standardized floral-knot suppression test, demonstrating the presence of EPF, which is most active during the first trimester of pregnancy and decreases with increasing gestational age until it disappears 8 weeks before delivery. Also measured before and after 21 cases of miscarriage of pregnant women, abortion pre-blood