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目的探讨欣母沛在剖宫产同时行子宫肌瘤剔除术中的疗效及安全性。方法前瞻性分析我院73例剖宫产同时行子宫肌瘤剔除术的患者,将其随机分为实验组(欣母沛组37例)及对照组(缩宫素组36例),比较两组在术中出血、住院天数、子宫下降高度、血红蛋白(Hb)下降,恶露持续时间方面的差异。结果欣母沛组的术中出血、血红蛋白(Hb)下降和恶露持续时间明显低于缩宫素组(均为P<0.05),术后子宫下降高度则明显高于缩宫素组(P<0.05)。欣母沛组的不良反应高于缩宫素组(P<0.05),但一般较轻,不需特殊处理。结论欣母沛应用于剖宫产术中行肌瘤剔除术在止血方面明显优于缩宫素,术后观察子宫收缩明显优于缩宫素组,有一定的应用前景。
Objective To investigate the efficacy and safety of Xin-Pei in the simultaneous cesarean section in myomectomy. Methods A prospective analysis of 73 patients with cesarean section who underwent myomectomy at the same time was randomly divided into experimental group (37 cases in Xin-Pei Group) and control group (36 cases in oxytocin group) Group differences in intraoperative bleeding, length of hospital stay, height of uterus, decreased hemoglobin (Hb), duration of lochia. Results The intraoperative bleeding, the decrease of hemoglobin (Hb) and the duration of lochia in Xinmupei group were significantly lower than those of oxytocin group (all P <0.05), and the postoperative uterine height was significantly higher than that of oxytocin group (P < 0.05). Adverse reactions in the Xin-Pei group were higher than those in the oxytocin group (P <0.05), but were generally mild and did not require special treatment. Conclusion Xin Mapei used in cesarean section line myomectomy in the hemostasis was better than oxytocin, postoperative observation of uterine contractions was significantly better than oxytocin group, has a certain application prospects.