论文部分内容阅读
目的:探讨急性乙醇中毒患者血液乙醇浓度(BAC)与超敏C反应蛋白(hs-CRP)水平的关系,分析BAC与hs-CRP水平的相关性。方法:分成急性乙醇中毒组(AL组)90例、对照组(NC组)30例,其中根据乙醇中毒程度及BAC值不同AL组又分为AL-Ⅰ组(轻度中毒)(BAC<200mg/L),AL-Ⅱ组(中度中毒)(200mg/L≤BAC<800mg/L),AL-Ⅲ组(重度中毒)(BAC≥800mg/L),每组30例,检测各组的hs-CRP浓度,并与NC组对照。分析BAC与hs-CRP浓度的相关性。结果:对照组与AL-Ⅰ组之间hs-CRP浓度差异无统计学意义(P>0.05)。其他各组两两之间的差异有统计学意义(P<0.05)。AL-Ⅰ组BAC与hs-CRP浓度无相关性(P>0.05),AL-Ⅱ组、AL-Ⅲ组BAC与hs-CRP浓度呈正相关(P<0.05)。结论:急性乙醇中毒轻度以上患者的BAC与hs-CRP浓度呈正相关,对于急性乙醇中毒患者hs-CRP是一项具有临床价值的检测项目。
Objective: To investigate the relationship between blood alcohol concentration (BAC) and high-sensitivity C-reactive protein (hs-CRP) in patients with acute alcoholism and to analyze the correlation between BAC and hs-CRP. Methods: 90 cases were divided into acute alcoholism group (AL group) and 30 cases of control group (NC group). According to the degree of alcoholism and different BAC value, AL group was divided into ALI group (mild poisoning) (BAC <200mg / L), AL-Ⅱgroup (moderate poisoning) (200mg / L≤BAC <800mg / L), AL-Ⅲgroup (BAC≥800mg / L) hs-CRP concentration, and compared with the NC group. Analysis of BAC and hs-CRP concentration correlation. Results: There was no significant difference in hs-CRP concentration between control group and AL-Ⅰ group (P> 0.05). The differences among the other groups were statistically significant (P <0.05). There was no correlation between the concentration of BAC and hs-CRP in AL-Ⅰ group (P> 0.05). There was a positive correlation between the concentration of BAC and hs-CRP in AL-Ⅱ group and AL-Ⅲ group (P <0.05). Conclusion: There is a positive correlation between BAC and hs-CRP in patients with mild alcoholism and hs-CRP in patients with acute alcoholism is a clinical value of the test.