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目的观察匹多莫德辅治新生儿感染性肺炎的临床疗效。方法将206例新生儿感染性肺炎患儿随机分为观察组和对照组各103例,2组均予常规综合治疗,对照组另予阿奇霉素序贯治疗,观察组在对照组的基础加用匹多莫德治疗。对比2组临床疗效、体温恢复正常时间、咳嗽缓解时间、住院时间。结果观察组总有效率为97.09%明显高于对照组的76.70%,差异有统计学意义(P<0.05)。2组均未发现有药物不良反应。观察组患儿体温恢复时间、咳嗽缓解时间以及住院时间均明显短于对照组,差异均有统计学意义(P<0.05)。结论匹多莫德辅助治疗新生儿感染性肺炎疗效确切,可有效缩短病程时间,药物不良反应少,是一种值得在临床应用与推广的治疗方案。
Objective To observe the clinical efficacy of pidotimod in the treatment of neonatal infectious pneumonia. Methods A total of 206 neonates with infectious pneumonia were randomly divided into observation group and control group, with 103 cases in each group. The two groups were given conventional treatment. The control group was treated with azithromycin sequential therapy. The observation group was divided into control group Domodt treatment. The clinical efficacy, body temperature returned to normal time, cough relief time and hospital stay were compared between the two groups. Results The total effective rate in the observation group was 97.09%, which was significantly higher than that in the control group (76.70%), the difference was statistically significant (P <0.05). No adverse drug reactions were found in the two groups. The body temperature recovery time, cough relief time and hospitalization time in the observation group were significantly shorter than those in the control group, with significant differences (P <0.05). Conclusion Pidotimod adjuvant treatment of neonatal infectious pneumonia is effective, which can effectively shorten the duration of the course of the adverse drug reactions, is a worthy of clinical treatment and promotion of the treatment.