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目的评价普拉洛芬滴眼液治疗白内障超声乳化术后干眼症的临床效果。方法选取在某院行白内障超声乳化术后1月出现干眼症的100例患者(100眼),随机分成两组,各50例(50眼),研究组给予普拉洛芬和玻璃酸钠滴眼液,对照组给予玻璃酸钠滴眼液,以泪膜破裂时间、染色评分、SchirmerⅠ试验及Saliabury干眼问卷评分作为评价指标,比较两组用药1周及2周后的疗效。结果治疗后研究组与对照组泪膜破裂时间均延长,染色评分及干眼问卷评分均降低(P<0.05),SchirmerⅠ无明显变化(P>0.05),且研究组的治疗效果优于对照组(P<0.05)。结论普拉洛芬滴眼液可以抑制眼表炎症,联合玻璃酸钠滴眼液治疗白内障超声乳化术后早期干眼症的效果优于单用玻璃酸钠滴眼液。
Objective To evaluate the clinical efficacy of pranoprofen eye drops in the treatment of dry eye after cataract phacoemulsification. Methods A total of 100 patients (100 eyes) with dry eye appeared in a hospital after cataract phacoemulsification were randomly divided into two groups (n = 50, 50 eyes). The study group was given pranoprofen and sodium hyaluronate Eye drops, the control group was given sodium hyaluronate eye drops, tear film break time, staining score, Schirmer Ⅰ test and Saliabury dry eye questionnaire score as the evaluation index, the two groups were treated 1 week and 2 weeks after the curative effect. Results After treatment, the rupture time of the tear film in the study group and the control group were prolonged, the scores of the staining score and the dry eye questionnaire were all decreased (P <0.05), Schirmer Ⅰ had no significant change (P> 0.05), and the treatment effect of the study group was better than that of the control group (P <0.05). Conclusions Pranoprofen eye drops can inhibit ocular surface inflammation. The combined effect of sodium hyaluronate eye drops in treating early dry eye after cataract phacoemulsification is better than that of sodium hyaluronate eye drops alone.