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目的了解福州市出生缺陷发生率、种类及变化趋势,为减少缺陷发生提供依据。方法对福州市12家监测医院住院分娩的围产儿出生缺陷监测相关资料进行回顾性分析。结果福州市2007—2012年围产儿出生缺陷发生率为113.0/万,男性高于女性;农村高于城镇;孕母年龄<20岁和≥35岁年龄组较高,出生缺陷导致的围产儿死亡占总围产儿死亡的30.3%,主要出生缺陷为外耳畸形、多指(趾)畸形、总唇裂、先天性心脏病(先心)及马蹄内翻足,神经管畸形发生率呈下降趋势。结论做好出生缺陷监测工作,加强三级预防,可减少出生缺陷的发生。
Objective To understand the incidence, types and trends of birth defects in Fuzhou and provide the basis for reducing the occurrence of defects. Methods Retrospective analysis was made on the monitoring data of birth defects in perinatal delivery in 12 monitoring hospitals in Fuzhou. Results The incidence of perinatal birth defects in Fuzhou from 2007 to 2012 was 113.0 / 000, higher in males than in females, higher in rural areas than in urban areas, higher in pregnant women <20 years and ≥35 years, perinatal deaths due to birth defects Accounting for 30.3% of the total perinatal deaths. The main birth defects were external ear deformity, multiple finger deformities, total cleft lip, congenital heart disease (congenital heart disease) and clubfoot, and the incidence of neural tube defects was on a downward trend. Conclusions Well monitoring of birth defects and strengthening tertiary prevention can reduce the incidence of birth defects.