论文部分内容阅读
目的探讨二维斑点追踪技术(speckle tracking imaging,STI)在评价原发性高血压(essential hypertension,EH)患者左心室纵向收缩功能中的临床应用价值。方法EH患者47例,其中左心室正常构型(normal left ventricular geometry,LVN)者24例(LVN组),左心室异常构型(abnormal left ventricular geometry,LVR)者23例(LVR组),同期体检健康者22例为对照组,3组均行超声心动图检查,分别获取心尖二腔心、三腔心及四腔心二维动态图像,应用STI技术测定左心室基底段(basal segment of left ventricle,Bas-LS)、中间段(middle segment of left ventricle,Mid-LS)、心尖段(apical segment of left ventricular,Ape-LS)纵向收缩峰值应变及左心室整体纵向应变峰值(systolic peak global longitudinal strain,GLS),并进行比较。结果 LVN组、LVR组Bas-LS[(-20.35±3.58)%、(-14.91±3.62)%]、Mid-LS[(-22.56±3.65)%、(-16.90±4.13)%]、Ape-LS[(-25.45±4.61)%、(-19.49±4.89)%]及GLS[(-22.89±3.94)%、(-17.30±4.21)%]均低于对照组[(-22.01±4.02)%、(-24.35±3.98)%、(-28.26±5.45)%、(-24.87±4.46)%],LVR组Bas-LS、Mid-LS、Ape-LS及GLS均低于LVN组,差异均有统计学意义(P<0.05)。结论 EH患者尤其是LVR者左心室纵向收缩功能下降,STI技术可定量评价EH患者左心室纵向收缩功能。
Objective To investigate the clinical value of two-dimensional speckle tracking imaging (STI) in evaluating left ventricular longitudinal systolic function in patients with essential hypertension (EH). Methods Forty-seven patients with EH were enrolled in this study. Twenty-four patients (LVN group) with normal left ventricular geometry (LVN), 23 patients with abnormal left ventricular geometry (LVR) Twenty-two healthy subjects were selected as control group. The echocardiography was performed in all three groups. Two-dimensional dynamic images of apical two-chamber, three-chamber and four-chamber were obtained respectively. The basal segment of left Ventricle, Bas-LS, middle segment of left ventricle (Mid-LS), apical segment of left ventricular (Ape-LS) and systolic peak global longitudinal peak strain, GLS) and compared. Results In the LVN group, the values of Bas-LS [(- 20.35 ± 3.58)%, (-14.91 ± 3.62)%], Mid-LS [(- 22.56 ± 3.65)%, (-16.90 ± 4.13)%] (-22.01 ± 4.02)% of the control group [(-25.45 ± 4.61)%, (-19.49 ± 4.89)%] and GLS [(-22.89 ± 3.94)%, (-17.30 ± 4.21)%] (-24.35 ± 3.98)%, (-28.26 ± 5.45)% and (-24.87 ± 4.46)%, respectively. The levels of Bas-LS, Mid-LS, Ape-LS and GLS in LVR group were lower than those in LVN group Statistical significance (P <0.05). Conclusion Longitudinal left ventricular systolic function in patients with EH, especially LVR, is decreased. STI can be used to quantitatively evaluate left ventricular longitudinal systolic function in patients with EH.