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目的探讨宫颈非典型鳞状上皮细胞(ASC)不除外高度病变(ASC-H)的临床意义及管理。方法回顾性分析成都市妇女儿童中心医院2013-2015年间用宫颈液基细胞学(LCT)方法检出的137例ASC-H,对比其阴道镜检查、组织学结果,初步分析其临床意义及各年龄段发现CINⅡ及以上病变的几率。结果在137例ASC-H病例中,阴道镜检查发现42例高度及以上病变,组织学显示:低度及以下病变55例,高度及以上病变82例;30~50岁之间组织学发现高度及以上病变的几率最高,60岁以上病变的几率最低。结论宫颈细胞学ASC-H具有较高的高度上皮内病变(HSIL)预测值,对ASC-H阴性病例应给予高度关注及恰当的处理。
Objective To investigate the clinical significance and management of nonclassified cervical squamous cell carcinoma (ASC-H) without extracranial lesions (ASC-H). Methods A retrospective analysis of 137 cases of ASC-H detected by cervical liquid-based cytology (LCT) from 2013 to 2015 in Chengdu Women and Children’s Central Hospital was performed. The colposcopy and histological results were compared and the clinical significance and Age found CIN Ⅱ and above the chances of disease. Results In 137 cases of ASC-H cases, colposcopy found 42 cases of height and above lesions, histology showed: 55 cases of low and below lesions, 82 cases of height and above lesions; 30 to 50 years old histological height And the highest risk of disease, the lowest risk of disease over the age of 60. Conclusion Cervical cytology ASC-H has a high predictive value of high intraepithelial lesion (HSIL), which should be given high attention and appropriate treatment for ASC-H negative cases.