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重症恶性疟疾和有合并症的恶性疟疾都需用速效抗疟药治疗.一旦临床确诊,就要给药。在治疗的初期,病人临床状况许可的情况下尽可能使用口服。作用较慢的抗疟药如四环素和法西达可作为辅助用药,但不宜单独使用或作为早期治疗使用。一般情况下,喹啉类的抗疟药治疗范围较窄,然而对药物的剂量、途径、速度和次数都需小心谨慎,但很少有严重的副作用。抗疟药绝对不能采用大剂量的静脉注射.氯喹(Chloroquine):在亚洲、南美洲和非洲的很多地区,恶性疟对氯喹产生了抗性,而在西非的一些国家,氯喹仍是
Severe cases of falciparum malaria and comorbid malignant malaria need to be treated with the fast-acting antimalarial drug, which should be given once clinically diagnosed. In the initial treatment, the patient’s clinical conditions permit the use of oral as much as possible. Slower anti-malarial drugs such as tetracycline and faxidac can be used as adjuvant drugs, but should not be used alone or as an early treatment. In general, quinolines have a narrower spectrum of anti-malarial treatments, however, care should be taken with respect to the dose, route, speed, and frequency of the drug, with few serious side effects. Antimalarial drugs must not be given in large doses intravenously Chloroquine: Plasmodium falciparum is resistant to chloroquine in many parts of Asia, South America and Africa, while in some West African countries chloroquine is still