论文部分内容阅读
经多种抗癫痫药治疗不能完全控制发作的Ｌｅｎｎｏｘ－Ｇａｓｔａｕｔ综合征１５例，男１２例，女３例，发病年龄平均为２．０７±１．３５岁，平均病程为４．５±３．７５年，其中隐原性１例，症状性１４例，１３例脑ＣＴ示脑萎缩或钙化，应用拉莫三嗪添加治疗１２周后，发作频度由（１１１．８６±８６）次／月减少为（４５．８±３６）次／月，具有显著性差异，治疗后总有效率为６６．６７％，治疗过程中未见明显不良反应。
15 cases of Lennox-Gastaut syndrome, which can not be completely controlled by many kinds of antiepileptic drugs, including 12 males and 3 females, mean age of onset is 2.07 ± 1.35 years old and average duration is 4.5 ± 3. 75 years, of which 1 cases of cryptogenic, symptomatic 14 cases, 13 cases of brain CT showed brain atrophy or calcification, application of lamotrigine 12 weeks after treatment, the frequency of seizures by (111.86 ± 86) times / month Reduced to (45.8 ± 36) times / month, with a significant difference, the total effective rate after treatment was 66.67%, no obvious adverse reactions in the course of treatment.