论文部分内容阅读
尽管外科和放疗技术的改进,食道上皮癌的子后仍不理想。初次诊断为食道癌而能手术的病人约占全部病人的30-50%,这部分病人用单独外科或放疗时,5年存活率不过5-20%。当外科与术前放疗结合时可提高切除率,但5年存活率仍在20%以下。晚期病人的化疗也不理想,导致一些人提出放疗与化疗相结合。本文报告了1965-1979年MSKCC收治的110例可手术的食道癌病人,行综合治疗。其中1965-1976年收治的76例用术前放疗加手术。术前放疗用二种方法:①大多数为“长程”放疗,4000-6000rad/4-6w,手术于开始照射后8周进行;②少数为“短程”放疗,2000rad/5天,放疗后立即手术。均用~(60)Co或直线加速器。1976年以后收治的34例用
Despite advances in surgical and radiotherapy techniques, the sub-epidermis of esophageal cancer is still not ideal. Patients who are diagnosed as esophageal cancer for the first time account for about 30-50% of all patients. In this group of patients, surgery or radiotherapy alone, the 5-year survival rate is only 5-20%. When surgery combined with preoperative radiotherapy can increase the resection rate, but the 5-year survival rate is still below 20%. The chemotherapy for late-stage patients was also unsatisfactory, leading some to propose a combination of radiotherapy and chemotherapy. This article reports on 110 cases of operable esophageal cancer patients treated by MSKCC from 1965 to 1979 with comprehensive treatment. Of these, 76 cases were treated with preoperative radiotherapy plus surgery from 1965 to 1976. Preoperative radiotherapy with two methods: 1 Most of the “long-range” radiotherapy, 4000-6000rad/4-6w, surgery performed 8 weeks after the start of irradiation; 2 a few “short-range” radiotherapy, 2000rad/5 days, immediately after radiotherapy surgery. Both use ~(60)Co or linear accelerators. 34 cases taken after 1976