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我院自1993年9月以来,采用抗T淋巴细胞单克隆抗体(ATA)治疗小儿再生障碍性贫血12例,取得较好疗效。 治疗方法:患儿先口服黄连素、克霉唑,用朵贝尔氏液嗽口,复方薄荷油滴鼻。3天后用ATA做皮试,待阴性反应后,根据患儿T淋巴细胞亚群结果,选用以下两种方案:①T_4/T_3大致正常组:给予抗CD_35～10mg,氟美松3～5mg,加入生理盐水300ml中静脉滴注,每日1次,连用5～10次。②T_4/T_3倒置组:给予抗CD_35～10mg,氟美松3～5mg,加入生理盐水300ml中静脉滴注,
Our hospital since September 1993, the use of anti-T lymphocyte monoclonal antibody (ATA) treatment of pediatric aplastic anemia in 12 cases, and achieved good results. Treatment: children with oral berberine, clotrimazole, with Bell wash mouth, Compound Peppermint intranasal. 3 days after the skin test with ATA, negative reaction, according to the results of children with T lymphocyte subsets, the following two options: ① T_4 / T_3 roughly normal group: anti-CD_35 ~ 10mg, 3 ~ 5mg dexamethasone, add Saline 300ml intravenous infusion, 1 day, once every 5 to 10 times. ② T_4 / T_3 inversion group: given anti-CD_35 ~ 10mg, flumestans 3 ~ 5mg, added 300ml of normal saline intravenous infusion,