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目的:研究烟雾病(moyamoya disease,MMD)的临床及影像学特征。方法:回顾性分析5例烟雾病患者,分析其临床及影像学特点。结果:本组病例既往均无阳性病史,中、青年起病,男性居多,均以缺血性脑血管病起病,肢体瘫痪不重,经颅多普勒(TCD)及头颅核磁改变明显,数字减影血管造影(DSA)检查均存在血管闭塞及侧支开放,烟雾血管网形成,1例MRA证实烟雾血管网形成。结论:对于无既往史的中、青年脑卒中患者,要考虑MMD的可能,需完善TCD、头核磁检寻找证据,最后完善数字减影血管造影确诊。
Objective: To study the clinical and imaging features of moyamoya disease (MMD). Methods: A retrospective analysis of 5 patients with moyamoya disease, analysis of its clinical and imaging features. Results: The past cases of this group had no history of positive disease, middle and young onset, the majority of men, all with ischemic cerebrovascular disease onset, limb paralysis is not heavy, transcranial Doppler (TCD) and cranial MRI changes significantly, Digital subtraction angiography (DSA) examination of both vascular occlusion and open lateral collateral, smoke vascular network formation, MRA confirmed by one case of smoke vascular network formation. CONCLUSIONS: For stroke patients with no previous history of middle and young age, the possibility of MMD should be considered, the TCD needs to be improved, the scintigraphy should be searched for evidence, and finally digital subtraction angiography should be performed to confirm the diagnosis.