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目的总结胸腔镜辅助非小细胞肺癌(NSCLC)手术的近期疗效。方法Ⅰa~Ⅱa期NSCLC患者75例行肺癌根治术。其中,胸腔镜辅助手术(VATS)组36例,开胸手术(OS)组39例。比较两组手术相关指标,评估术后6个月内肺功能和肺癌患者生存质量测定量表(FACT-L)评分。结果与OS组相比,VATS组术中出血量和术后第1天胸腔引流量少,术后首次下床时间早,住院时间短,术后3d内血浆超敏C反应蛋白水平低,术后6个月内肺功能较好,FACT-L评分高(P<0.05)。结论与开胸手术相比,胸腔镜辅助行Ⅰa~Ⅱa期NSCLC手术治疗创伤小,对肺功能损害小,生活质量较高。
Objective To summarize the short-term results of thoracoscopic assisted non-small cell lung cancer (NSCLC) surgery. Methods A total of 75 patients with stage Ⅰa-Ⅱa NSCLC underwent radical resection of lung cancer. Thirty-six patients underwent thoracoscopic surgery (VATS) and 39 patients underwent thoracotomy (OS). The operation-related indexes of the two groups were compared to evaluate the FACT-L score of lung function and lung cancer patients within 6 months postoperatively. Results Compared with the OS group, the VATS group had less intraoperative blood loss and less chest drainage on the first postoperative day, the time to first bed was shorter, the length of hospital stay shorter, and the level of plasma high-sensitivity C-reactive protein Pulmonary function was better in the first 6 months and FACT-L was higher (P <0.05). Conclusions Compared with thoracotomy, thoracoscopic assisted surgery of stage Ⅰa ~ Ⅱa NSCLC has less trauma, less damage to lung function and higher quality of life.