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目的:提高对川崎病(KD)的临床认识,早诊断、早治疗以减少冠状动脉损害的发生。方法:对上虞市妇幼保健院儿科2001~2011年收治的116例川崎病患儿进行回顾性分析和总结。结果:116例患儿中典型90例,不完全26例,合并冠状动脉损害23例,冠状动脉损害发生率为19.83%。结论:川崎病临床症状均非特异性,且表现不一,尤其是不完全川崎病临床不典型,可以结合实验室检查如血白细胞、CRP、血沉及血小板动态变化,做到早诊断早治疗减少冠脉损害发生。男性、发病时年龄小、IKD、发热持续时间长、大剂量丙种球蛋白使用晚、WBC、CRP显著增高与冠脉损害发生有明显关系,必须高度关注,及时超声心动图检查观察冠脉损害情况。
Objective: To improve the clinical knowledge of Kawasaki disease (KD), early diagnosis and early treatment to reduce the occurrence of coronary artery lesions. Methods: A retrospective analysis and summary of 116 children with Kawasaki disease admitted to Shangyu Maternal and Child Health Care Hospital from 2001 to 2011 were conducted. Results: Among the 116 cases, 90 cases were typical and 26 cases were incomplete. Coronary artery lesions were found in 23 cases. The incidence of coronary artery lesions was 19.83%. Conclusion: Kawasaki disease clinical symptoms are nonspecific, and the performance is different, especially incomplete clinical Kawasaki disease is not typical, combined with laboratory tests such as white blood cells, CRP, erythrocyte sedimentation rate and platelet dynamic changes, early diagnosis and early treatment to reduce the crown Pulse damage occurs. Men, age at onset, IKD, long duration of fever, late use of high-dose gamma globulin, WBC, CRP was significantly higher and coronary lesions have a significant relationship must be highly concerned, timely echocardiography to observe coronary lesions .