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将我院１９８７～１９９２年施行乳腺癌根治性切除的术前肿块局部切除组１０６例和直接一次性根治术组１４３例患者的预后进行对比研究。结果发现，术前肿块局部切除组之术后复发率、远处转移率及３和５年生存率分别小于１６．０％、２６．４％及７９．２％和７１．７％，而直接一次性根治术组则分别为４．９％、１６．１％及８９．５％和８２．５％，两组患者４项预后指标比较均存在显著性差异（Ｐ值分别小于０．０１、０．０５、０．０５、０．０５）。本结果表明，术前肿块局部切除将对乳腺癌患者预后造成严重影响，故术前肿块局部切除不宜轻易施行。
In our hospital, from 1987 to 1992, the prognosis of 106 patients undergoing radical resection of breast cancer before radical resection and 143 patients undergoing direct radical surgery were compared. The results showed that the postoperative recurrence rate, distant metastasis rate, and 3- and 5-year survival rates in the local resection group were less than 16.0%, 26.4%, 79.2%, and 71.7%, respectively. The one-time radical surgery group was 4.9%, 16.1%, and 89.5% and 82.5%, respectively. There were significant differences in the four prognostic indicators between the two groups (P values less than 0.01, respectively). 0.05, 0.05, 0.05). The results show that the local resection of the preoperative lump will have a serious impact on the prognosis of patients with breast cancer, so the local resection of the preoperative lump should not be easily implemented.