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药物性食管损伤是常由腐蚀性药物引起,一般不见于治疗剂量的临床用药。但是由于食管本身的问题,如受压狭窄、运动障碍、返流等原因,或因吞咽药片或胶囊时没有用足够的水送服,或在躺卧的体位服药,易使药物在食管滞留时间延长,一些治疗剂量的临床用药亦可导致食管损伤。 1970年Pemberton报道二尖瓣置换术后十日出现食管狭窄,食管镜检查见食管下1/3有溃疡性病灶且该区有白色粉状物,考虑为慢释放型氯化钾片(慢钾片),才引起了人们的
Drug-induced esophageal damage is often caused by corrosive drugs, generally not seen in the treatment of clinical dose. However, due to esophageal problems, such as compression narrow, dyskinesia, reflux and other reasons, or not swallowed tablets or capsules with enough water to serve, or lying in the position of medication, easy to make drugs in esophageal residence time Prolongation, some therapeutic doses of clinical medication can also lead to esophageal damage. In 1970, Pemberton reported esophageal stenosis ten days after mitral valve replacement. Esophagoscopy revealed ulcerative lesions in the lower third of the esophagus and white powder in the area, considered as slow release potassium chloride tablets (slow potassium Film), it caused people’s