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为了确定Ⅱ期和Ⅲ期直肠癌患者术后辅助放化疗的最佳顺序,Kim TW、Lee JH、Lee JH等人进行了长达10年的随访研究。研究分为两组,一组实施早期术后辅助放化疗(早期组),另一组实施晚期术后辅助放化疗(晚期组)。两组的术后放化疗均包括8个化疗周期,并在间隔4周之后进行放射治疗。研究发现,较晚进行术后辅助放化疗的患者复发率相比于早期组较
To determine the optimal order of postoperative adjuvant chemoradiotherapy for patients with stage II and III rectal cancer, a follow-up study of 10 years was performed by Kim TW, Lee JH, Lee JH, et al. The study was divided into two groups. One group received adjuvant radiotherapy and chemotherapy after early stage (early stage), and the other group received adjuvant chemotherapy and radiotherapy after advanced stage (late stage). Both groups received postoperative chemoradiation including 8 cycles of chemotherapy and radiotherapy after 4 weeks. The study found that patients receiving adjuvant chemoradiation later relapse rate than the early group