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目的:探讨肝硬化腹水并发自发性细菌性腹膜炎(SBP)患者感染菌群分布及药敏情况。方法:回顾性分析78例临床诊断为肝硬化腹水并发SBP患者的临床资料、菌群分布及药敏结果。结果:78例患者中31例分离出病原菌,分离率39.74%,菌群分布以革兰阴性菌居多,占61.29%,分离率在前4位的病原菌依次是大肠埃希菌、金黄色葡萄球菌、克雷伯菌、凝固酶阴性葡萄球菌(CNS)。结论:肝硬化腹水患者易并发SBP,应根据药敏结果合理选择抗生素,并针对危险因素及高危人群采取有效的预防措施,从而降低SBP的发生率。
Objective: To investigate the distribution of bacterial infection and drug susceptibility in patients with cirrhotic ascites complicated by spontaneous bacterial peritonitis (SBP). Methods: A retrospective analysis of 78 cases of clinical diagnosis of cirrhotic patients with ascites SBP clinical data, the distribution of bacteria and susceptibility results. Results: Among the 78 patients, the pathogenic bacteria were isolated from 31 patients and the isolation rate was 39.74%. The majority of gram-negative bacteria were found in the flora, accounting for 61.29% of the total. The pathogenic bacteria with the highest isolation rate were Escherichia coli, Staphylococcus aureus , Klebsiella, coagulase-negative staphylococci (CNS). Conclusion: Patients with cirrhosis and ascites complicated with SBP should be based on drug susceptibility results reasonable selection of antibiotics, and for risk factors and high risk populations to take effective preventive measures to reduce the incidence of SBP.