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目的:探讨胰岛素抵抗在多囊卵巢综合征的临床价值,以供参考。方法 :将本院2012年7月至2013年6月收治的多囊卵巢综合征患者60例作为观察组,以同期在我院体检的健康育龄期女性60例作为对照组。对比两组在胰岛素抵抗发生率的差异性。将观察组患者随机分为A、B两组。A组接受常规促排卵治疗,B组在此基础上加用胰岛素增敏剂治疗,对比两组治疗效果的差异性。结果:与对照组对比,观察组胰岛素抵抗发生率明显较高,组间差异经统计学分析后认为有意义(P<0.05)。与A组对比,B组总有效率明显较高,组间差异经统计学分析后认为有意义(P<0.05)。结论 :胰岛素抵抗与多囊卵巢综合征存在一定的相关性,在多囊卵巢综合征的临床治疗过程中适当辅以胰岛素增敏剂可有效提高治疗效果。
Objective: To investigate the clinical value of insulin resistance in patients with polycystic ovary syndrome for reference. Methods: 60 patients with polycystic ovary syndrome who were treated in our hospital from July 2012 to June 2013 were selected as the observation group and 60 healthy women of childbearing age who were in our hospital during the same period as the control group. The difference between the two groups in the incidence of insulin resistance was compared. The observation group patients were randomly divided into A, B two groups. A group received routine ovulation induction treatment, B group on this basis with insulin sensitizer treatment, the difference between the two groups were compared. Results: Compared with the control group, the incidence of insulin resistance in the observation group was significantly higher, and the difference between the groups was considered statistically significant (P <0.05). Compared with group A, the total effective rate in group B was significantly higher, and the difference between groups was considered statistically significant (P <0.05). Conclusion: There is a certain correlation between insulin resistance and PCOS. Appropriate supplementation with insulin sensitizer during the clinical treatment of PCOS can effectively improve the therapeutic effect.