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甲苯二异氰酸酯是异氰酸酯类化合物中最常用的一种,简称(TDI)。其主要用途是制造聚氨酯树脂及其泡沫塑料,制造和使用TDI都可能不同程度地接触TDI。 TDI属低毒类,在较高浓度下(0.5～5ppm)对粘膜有刺激作用,可导致支气管炎、支气管肺炎,甚至肺水肿。另一方面,即使在极低浓度下(0.0012～0.02ppm)也能对少数人诱发哮喘或过敏性肺炎。兹报告TDI引起哮喘2例如下。 病例1宋x,女,31岁,某聚氨酯塑料厂工人。患者于1980年开始直接接触少量TDI,起初自觉憋气,但不喘,脱离接触则症状消失。1982年7月份,TDI桶盖脱落,患者闻到强烈的TDI气味后立即咳
Toluene diisocyanate is the most commonly used isocyanate compounds, referred to as (TDI). Its main purpose is to manufacture polyurethane resins and their foams, TDI being made and used to varying degrees with TDI. TDI is a low-toxic species that stimulates mucous membranes at higher concentrations (0.5-5 ppm) and can cause bronchitis, bronchopneumonia and even pulmonary edema. On the other hand, asthma or allergic pneumonia can be induced in a few people even at extremely low concentrations (0.0012 to 0.02 ppm). We report the following two cases of TDI-induced asthma. Case 1 Song x, female, 31 years old, a polyurethane plastic factory workers. The patient started to have direct contact with a small amount of TDI in 1980, initially feeling suffocated but not relieved and disappeared after contact. July 1982, TDI lid off, the patient smelled strong TDI smell immediately cough