,Crystal structure of HLA-B*5801, a protective HLA allele for HIV-1 infection

• 作 者: Xiaolong Li Pedro A.Lamothe Robert Ng Shutong XU Maikun Teng Bruce D.Walker Jia-huai Wang
• 机 构: School of Life Sciences, University of Science and Technology of China, Hefei 230027, China“,” Depar
• 出 处: 蛋白质与细胞
• 发表日期: 2016年10期

Dear Editor,Conquering the AIDS epidemic remains one of the most challenging global health issues.Despite impressive advances in combination antiretroviral therapy (cART) to treat HIV,and substantial progress in the development of prevention interventions,a protective vaccine has remained elusive.Successful vaccination will require the immune system to function better than it does in natural infection,in which the infection invariably becomes chronic.