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研究胎儿窘迫时脐血脂类的变化特点,应用酶法和免疫透射比浊法测定了33例胎儿窘迫脐动脉血清脂蛋白及载脂蛋白A1和B浓度变化,并以77例无胎儿窘迫的正常脐血做对照分析。其结果:胎儿窘迫组脐血胆固醇(CHOL),低密度脂蛋白胆固醇(LDL-C),载脂蛋白B(APOB)较正常对照组明显减少,差异显著(P<0.05)。而甘油三酯(TG)则较正常对照组升高,差异显著(P<0.05)。提示检测脐血脂蛋白和载脂蛋白为胎儿窘迫提供了新的诊断方法
To study the changes of umbilical blood lipids during fetal distress. The concentrations of serum lipoproteins and apolipoproteins A1 and B in 33 cases of fetal distress were measured by enzyme immunoassay and immunoturbidimetric assay, and 77 cases with normal fetal distress Cord blood control analysis. Results: The levels of CHOL, LDL-C and APOB in fetal distress group were significantly lower than those in normal control group (P <0.05). Triglyceride (TG) was higher than the normal control group, the difference was significant (P <0.05). Prompt detection of cord blood lipoprotein and apolipoprotein provides a new diagnostic method for fetal distress