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To study the relationship between ulcer recurrence and %Helicobacter Pylori%. 147 patients with peptic ulcer were divided into %H. Pylori% infected group and %H.pylori% uninfected group by rapid urease test、serum antibody examination and histopathology of gastric biopsy specimens. We assigned all patients to receive dual oral therapy with omeprazole 40 mg/day for 4 weeks and amoxicillin 2000 mg/day for 2 weeks. To all patients, repeated gastroscope was performed at 8 weeks and one year after beginning therapy to record whether the ulcer was cured. Endoscopic biopsy was also performed to dertermine %H.pylori% status. One year later, %H.pylori% positive patients had a higher ulcer recurrent rate than %H.pylori% negative patients(23.33% vs 2.70%; P=0.001). Ulcer recurrence was closely related to %H.pylori% infection. %H.pylori% was the risk factor for ulcer relapse.
To study the relationship between ulcer recurrence and % Helicobacter Pylori %. 147 patients with peptic ulcer were divided into % H. Pylori % infected group and % H.pylori % uninfected group by rapid urease test, serum antibody examination and histopathology of gastric biopsy specimens. We assigned all patients to receive dual oral therapy with omeprazole 40 mg / day for 4 weeks and amoxicillin 2000 mg / day for 2 weeks. To all patients, repeated gastroscope was performed at 8 weeks and one year after beginning therapy to record whether the ulcer was cured. Endoscopic biopsy was also performed to dertermine % H.pylori % status. One year later, % H.pylori % positive patients had a higher ulcer recurrent rate than % H.pylori % negative patients (23.33% vs 2.70%; P = 0.001). Ulcer recurrence was closely related to % H.pylori % infection. % H .pylori % was the risk factor for ulcer relapse.