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由于冠状动脉内血栓形成是心肌梗塞的原因,启发人们寻找一种安全、快速且有效的溶栓疗法。本文报告用尿激酶原(pro-uro-kinase)进行多中心试验的结果。方法病例的初选标准:(1)缺血性胸痛至少持续30分钟;(2)至少一个 ST 段抬高的导联上存在 R 波;(3)从胸痛发作至开始尿激酶原治疗不超过5小时;(4)没有进行溶栓疗法的常规禁忌症。合格者立即进行冠脉造影,但仅选择冠脉完全闭塞者(TIMI(?)级)作为研究对象,而冠脉内注硝酸甘油后冠脉痉挛解除者除外。本组共40(男34,女
Because coronary thrombosis is a cause of myocardial infarction, people are inspired to find a safe, rapid and effective thrombolytic therapy. This article reports the results of a multicenter trial using pro-uro-kinase. Methodology Primary Criteria: (1) Ischemic chest pain lasts for at least 30 minutes; (2) R wave is present on at least one ST segment elevation lead; (3) Urokinase treatment does not exceed 5 hours; (4) no routine contraindications to thrombolytic therapy. Coronary angiography was performed immediately, but TIMI (?) Grade was only selected as the study object, except for those who had coronary intracoronary nitroglycerin after coronary artery spasm. The group of 40 (male 34, female