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用一步法微囊包膜技术包裹新生猪胰岛，移植于８只糖尿病小鼠腹腔后约１周，小鼠血糖由移植前的＞１６．６７ｍｍｏｌ／Ｌ降至＜８．３３ｍｍｏｌ／Ｌ。然后将维持疗效１３０天以上小鼠的移植物取出作组织学检查。结果显示微囊内仍见边缘清晰的完整胰岛，且微囊胰岛无纤维包绕；而移植无微囊胰岛的对照组，正常血糖仅维持２周，移植物即被排斥。提示采用微囊化的胰岛异种移植，能有效地纠正糖尿病模型动物的高血糖，并明显地延长小鼠的存活期。说明此微囊具有免疫隔离作用，且有良好的生物膜性，能有效地避免宿主抗移植物的排异反应。
The newborn porcine islets were encapsulated by one-step microencapsulation and transplanted into the peritoneal cavity of 8 diabetic mice for about 1 week. The blood glucose of mice was reduced to> 8.33 mmol / L from> 16.67 mmol / L before transplantation. The grafts maintained for more than 130 days in the mice were then removed for histological examination. The results showed that intact islets with clear edges were still seen in the microcapsules, and the microcapsulated islets were surrounded by no fibers. In the control group without microcapsular islets, the normal blood glucose was only maintained for 2 weeks and the graft was rejected. Prompted the use of microencapsulated islet xenografts, can effectively correct the diabetic model animals high blood sugar, and significantly prolong the survival of mice. It shows that this microcapsule has the function of immune isolation and has good biofilm, which can effectively prevent the rejection of the host against the graft.