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目的:了解PHA—L、DSA这两种植物血凝素在人类胎盘早期绒毛、葡萄胎、侵蚀性葡萄胎和绒癌组织中的表达、方法;使用免疫胶体金技术,检测组织中的植物血凝素受体强度。结果:在人类早期股金组织中,植物血凝素受体仅在纺毛表面有一些轻微的染色,而葡萄胎、侵蚀性葡萄胎和城癌组织中的染色却非常强.统计表明、两种血凝素受体在正常组织与葡萄胎、侵蚀性葡萄胎和绒癌三组之间存在极显著差别(P<0.001),葡萄胎与侵蚀性葡萄胎和绒癌之间也分别存在着显著差别(P<0.05),但侵蚀性葡萄胎与绒癌两组之间,差别不明显(P>0.05)。结论;滋养细胞表面的PHA-L染色强.表明了其组织中的β1,6寡糖支链的增加,因而这些细胞具有侵蚀子宫和其它器官的能力。
Objective: To understand the expression and methods of PHA-L and DSA lectins in human placenta at the early stage of villus, hydatidiform mole, aggressive hydatidiform mole, and choriocarcinoma; use immunogold-colloid technique to detect vegetative blood in tissues. Glucocorticoid receptor intensity. RESULTS: In the early human femoral tissues, phytohemagglutinin receptors stained only slightly on the spinning surface, whereas staining in hydatidiform moles, aggressive moles, and urban cancers was very strong. Statistics showed that The hemagglutinin receptors were significantly different between normal tissues and hydatidiform moles, aggressive moles, and choriocarcinomas (P<0.001), and there were also differences between hydatidiform moles and aggressive moles and choriocarcinomas. Significant difference (P<0.05), but there was no significant difference between aggressive moles and choriocarcinomas (P>0.05). Conclusion: PHA-L staining on the surface of trophoblast cells is strong, indicating an increase in β1,6 oligosaccharide branches in their tissues, and thus these cells have the ability to erode the uterus and other organs.