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【目的】探讨内镜下尼龙绳结扎术在预防胃肠道宽基及粗蒂息肉电凝切术并发症的作用及意义。【方法】74例患者随机分为两组，观察组38例采用先内镜下尼龙绳结扎胃肠道宽基底及粗蒂息肉，后行息肉电凝切术；对照组36例单纯内镜下息肉电凝切术。观察并比较两组术中出血、穿孔情况及术后14 d内消化道出血、息肉残留等并发症情况。【结果】观察组14 d内出现并发症2例（出血1例，息肉残留1例）；对照组出现并发症10例（出血6例，穿孔2例，息肉残留2例），两组比较有显著性差异（ P ＜0．05）。【结论】内镜下尼龙绳结扎术在可有效预防胃肠道宽基及粗蒂息肉电切术后并发症的发生，具有疗效肯定、安全等优点。“,”[Objective] To evaluate the preventive effectiveness of endoscopic nylon endoloop for complications during electric coagulation electrocision of broad base and thick pedicle polyp in gastrointestinal tract .[Methods]A total of 74 patients were randomly divided into two groups .For treatment group ( n =38) ,endoscopic nylon endoloop was applied before electric coagulation electrocision of broad base and thick pedicle polyp in gastrointesti‐nal tract .For control group ( n=36) ,only endoscopic electric coagulation electrocision was performed .The oc‐currences of hemorrhages or perforation during operations and hemorrhages of digestive tract or residual polyp up until Week 2 were observed and recorded .[Results] At Week 2 after treatment ,complications occurred in treat‐ment group (hemorrhage ,n=1;residual polyp ,n=1) and control group (hemorrhage ,n=6 ;perforation ,n =2;residual polyp ,n =2) .Statistically significant differences existed between two groups ( P <0 .05) .[Conclu‐sion]:Endoscopic nylon endoloop can effectively and safely prevent the occurrences of complications during electric coagulation electrocision of broad‐base‐and‐thick‐pedicle polyps in gastrointestinal tract .