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目的 初步探讨内镜诊断反流性食管炎 (reflux esophagitis,RE)的临床价值。方法 根据胃食管反流症状并经内镜诊断的 RE病例 (A组 ,2 4例 )分别行食管测压及 2 4h p H监测并与正常对照组 (B组 ,2 0例 )比较。结果 A组与 B组比较 ,下食管括约肌静息压 (lower esophageal sphincter pressure,L ESP) (P <0 .0 1)、原发蠕动收缩波幅(P <0 .0 5 )及 2 4h p H监测 6项指标 (P <0 .0 1)差异均有显著性。RE的严重程度与 L ESP、总 p H<4时间百分率、立位 p H<4时间百分率、仰卧位 p H<4时间百分率 (均 P <0 .0 1)、大于 5 min反流次数 (P <0 .0 0 1)及反流最长时间(P <0 .0 5 )等相关。结论 内镜对于 RE的诊断具有较大的临床价值 ,是值得推荐的诊断方法
Objective To investigate the clinical value of endoscopic diagnosis of reflux esophagitis (RE). Methods According to the gastroesophageal reflux symptoms and endoscopic diagnosis of RE cases (A group, 24 cases) were esophageal manometry and 24 h p H monitoring and compared with the normal control group (B group, 20 cases). Results Compared with group B, lower esophageal sphincter pressure (L ESP) (P <0.01), primary peristaltic contractility amplitude (P <0.05) and 24 h p H Monitoring 6 indicators (P <0. 01) differences were significant. The severity of RE and L ESP, total p H <4 time percentage, standing p H <4 time percentage, supine position p H <4 time percentage (all P <0.01), greater than 5 min reflow frequency P <0. 01) and the longest reflux time (P <0. 05) and other related. Conclusion Endoscopic diagnosis of RE has great clinical value, it is recommended diagnostic method