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目的:了解围产期孕妇的凝血和纤溶状态,预防孕妇在分娩过程中及产后大出血而导致的急性DIC及血栓栓塞性疾病的发生。方法:对510例围产期孕妇(孕38周以上)使用真空管静脉采血后进行血浆D-二聚体和纤维蛋白原的检测,并与正常非妊娠妇女50例做对照。结果:围产期孕妇的血浆D-二聚体和纤维蛋白原都明显高于正常非妊娠女性。结论:围产期孕妇血液呈现相对高凝及继发性纤溶增强状态,倾向于血栓形成和DIC的发生,动态监测血浆D-二聚体和FIB能及早发现和预防围产期孕妇DIC和血栓栓塞性疾病。
Objective: To understand the coagulation and fibrinolytic status of perinatal pregnant women and to prevent the occurrence of acute DIC and thromboembolic diseases in pregnant women during childbirth and postpartum hemorrhage. Methods: The plasma D-dimer and fibrinogen were detected in 510 cases of perinatal pregnant women (38 weeks of age or more) by using the venous blood of vacuum tubes and compared with 50 cases of normal non-pregnant women. Results: Plasma D-dimer and fibrinogen in perinatal pregnant women were significantly higher than those in normal non-pregnant women. Conclusion: Perinatal pregnant women showed relatively hypercoagulable and secondary fibrinolytic state with increased blood coagulation, thrombosis and DIC. Dynamic monitoring of plasma D-dimer and FIB could early detect and prevent perinatal DIC Thromboembolic disease.